A major new study suggests that the shingles vaccine may do more than protect against painful rashes—it could also reduce the risk of serious cardiovascular events. The world’s first global systematic review and meta-analysis found that adults who received the herpes zoster vaccine had an 18% lower risk of heart attack or stroke, with a 16% reduction observed in people over 50.
Researchers analyzed 19 studies, including observational research and one randomized controlled trial, and the findings will be presented at the European Society of Cardiology congress in Madrid. While the results are promising, experts caution that most of the evidence comes from observational studies, which cannot prove direct cause and effect. Scientists believe the benefit may be linked to reduced inflammation, since shingles is known to trigger inflammatory processes tied to cardiovascular disease.
The study’s authors and independent cardiology experts agree that more research is needed, particularly to understand why younger adults may also see protective effects. In the meantime, vaccination continues to be viewed as a potential tool not only against infections but also in reducing broader cardiovascular risks. NHS England recently expanded shingles jab eligibility, opening access to an additional 300,000 people.
